Example sentences for: tyrosinase

How can you use “tyrosinase” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Here, we show increased IOP in mice lacking tyrosinase activity compared to otherwise genetically identical pigmented B6 mice.

  • The gene responsible for the ISA phenotype is tightly linked to the tyrosinase related protein 1 gene ( Tyrp1 ) [ 12], which also regulates coat color.

  • It has long been known that the sera of patients who suffer from melanoma or mammary carcinoma show higher tyrosinase activity than normal sera [ 35 ] but, to our knowledge, this is the first report of TYRP-1 expression in human breast duct epithelium.

  • Previously, we had demonstrated higher diagnostic accuracy in detecting and diagnosing melanoma micrometastases in sentinel lymph node using monoclonal antibodies to MART-1 (clone M2-7C10) and Melan-A (clone A103) in comparison to the traditionally used immunohistochemical markers, S-100 protein (S-100) and HMB-45 [ 6 ] . The cytoplasmic staining with these immunomarkers does not obscure the nuclear details and facilitates accurate interpretation of tumor cells, macrophages, and nevus cells in contrast to S-100 [ 6 12 ] . A monoclonal antibody to a third melanoma immunomarker, Tyrosinase (clone T311), showed an immunostaining pattern similar to MART-1 and Melan-A [ 13 ] .

  • The albino mice were homozygous and coisogenic for a mutant allele of tyrosinase ( Tyr c -2 J ) that arose on the otherwise pigmented B6 background.


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