Words similar to tyrosinase

Example sentences for: tyrosinase

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It has long been known that the sera of patients who suffer from melanoma or mammary carcinoma show higher tyrosinase activity than normal sera [ 35 ] but, to our knowledge, this is the first report of TYRP-1 expression in human breast duct epithelium.
The melanogenic enzymes tyrosinase, TYRP-1 and TYRP-2 are well-characterized differentiation antigens recognized by antibodies and T cells of patients with melanoma.
Previously, we had demonstrated higher diagnostic accuracy in detecting and diagnosing melanoma micrometastases in sentinel lymph node using monoclonal antibodies to MART-1 (clone M2-7C10) and Melan-A (clone A103) in comparison to the traditionally used immunohistochemical markers, S-100 protein (S-100) and HMB-45 [ 6 ] . The cytoplasmic staining with these immunomarkers does not obscure the nuclear details and facilitates accurate interpretation of tumor cells, macrophages, and nevus cells in contrast to S-100 [ 6 12 ] . A monoclonal antibody to a third melanoma immunomarker, Tyrosinase (clone T311), showed an immunostaining pattern similar to MART-1 and Melan-A [ 13 ] .
The gene responsible for the ISA phenotype is tightly linked to the tyrosinase related protein 1 gene ( Tyrp1 ) [ 12], which also regulates coat color.
The albino mice were homozygous and coisogenic for a mutant allele of tyrosinase ( Tyr c -2 J ) that arose on the otherwise pigmented B6 background.