Words similar to txk
Example sentences for: txk
How can you use “txk” in a sentence? Here are some example sentences to help you improve your vocabulary:
Btk is the prototypical member of the Tec family of non-receptor protein tyrosine kinases (PTKs) that includes Bmx, Itk, Tec and Txk [ 2, 3].
The combination of similar and distinct features is further supported by the observation that TXK can rescue phospholipase C-γ activation in BTK deficient DT40 cells, but fails to rescue a defect in apoptosis [ 42].
Rlk/Txk is a Tec related kinase that is predominantly expressed in cells of the T cell lineage [ 30, 31, 32].
Recently, we have found that Rlk/Txk can also be phosphorylated after TCR engagement [ 19].
In particular, we have found that Btk-deficient DT40 cells reconstituted with Txk, an atypical Tec family PTK, fail to undergo BCR-induced JNK activation (Tomlinson and Johnston, unpublished data) and apoptosis [ 13], but ERK activation is relatively normal [ 13].