Example sentences for: txa

How can you use “txa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Ibuprofen prevents the formation of TxA 2 , as well as platelet and leucocyte aggregation [ 12 21 ] . Fletcher et al.

  • Because PGI 2 and TXA 2 have opposing effects in vivo , we calculated the ratio of their metabolites (6-keto-PGF 1α :TXB 2 ) and found a significantly lower ratio in HF-IPF at baseline (0.

  • IL-1β-stimulated production of TXB 2 (stable metabolite of the active TXA

  • On the other hand, PGI 2 decreases vascular smooth muscle cell proliferation and collagen and glycosaminoglycane synthesis, via activation of adenylyl cyclase and subsequent production of cAMP [ 17 ] . Betaprost, an analog of PGI 2 , decreases procollagen I and III mRNA expression in cardiac fibroblasts [ 18 ] . These effects may counteract the profibrotic effects seen with TXA 2 and it is possible that an alteration of a "normal" physiologic balance between PGI 2 and TXA 2 could increase tendency towards fibrogenesis.

  • TxA 2 is a product of arachidonic acid and a potent platelet aggregator, whose levels increase during endotoxic shock.


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