Words similar to txa

Example sentences for: txa

How can you use “txa” in a sentence? Here are some example sentences to help you improve your vocabulary:

IL-1β-stimulated production of TXB 2 (stable metabolite of the active TXA
Because PGI 2 and TXA 2 have opposing effects in vivo , we calculated the ratio of their metabolites (6-keto-PGF 1α :TXB 2 ) and found a significantly lower ratio in HF-IPF at baseline (0.
We hypothesize that the lower PGI 2 :TXA 2 ratio seen in HF-IPF may be a phenotypic alteration that plays a role in the pathogenesis of IPF.
The effects of PGs on cell proliferation and collagen production have been widely studied in different cell types [ 13 14 15 16 17 26 ] . TXA 2 has been studied extensively because of its apparent role in atherosclerosis, due to its prothrombotic and mitogenic activities on vascular smooth muscle cells [ 15 16 ] . These mitogenic effects are potentiated by growth factors [ 15 16 27 28 ] . In vascular smooth muscle cells TXA 2 stimulates synthesis of bFGF and increases the expression of the proto-oncogenes c-fos , c-myc , and egr-1 , which are associated with entry into the cell growth cycle [ 15 ] . In addition, TXA 2 increases proliferation of fibroblasts [ 13 ] and smooth muscle-like glomerular mesangial cells [ 14 ] .
The above results suggest that a decreased PGI 2 :TXA 2 ratio could be a phenotypic alteration present in IPF fibroblasts, resulting in a loss of their capacity to autoregulate proliferation and extracellular matrix production.