Words similar to txa

Example sentences for: txa

How can you use “txa” in a sentence? Here are some example sentences to help you improve your vocabulary:

The ratio of PGI 2 to TXA 2 metabolites was lower in IPF fibroblasts at baseline and with IL-1β stimulation.
Ibuprofen prevents the formation of TxA 2 , as well as platelet and leucocyte aggregation [ 12 21 ] . Fletcher et al.
We hypothesize that the lower PGI 2 :TXA 2 ratio seen in HF-IPF may be a phenotypic alteration that plays a role in the pathogenesis of IPF.
The effects of PGs on cell proliferation and collagen production have been widely studied in different cell types [ 13 14 15 16 17 26 ] . TXA 2 has been studied extensively because of its apparent role in atherosclerosis, due to its prothrombotic and mitogenic activities on vascular smooth muscle cells [ 15 16 ] . These mitogenic effects are potentiated by growth factors [ 15 16 27 28 ] . In vascular smooth muscle cells TXA 2 stimulates synthesis of bFGF and increases the expression of the proto-oncogenes c-fos , c-myc , and egr-1 , which are associated with entry into the cell growth cycle [ 15 ] . In addition, TXA 2 increases proliferation of fibroblasts [ 13 ] and smooth muscle-like glomerular mesangial cells [ 14 ] .
It is important to mention that our experiments were conducted at similar passage levels (passage 6 to 8) in both groups, since senescence of fibroblasts is associated with a shift from the biosynthesis of PGI 2 to TXA 2 [ 24 25 ] . It is possible that the difference seen in our study between HF-IPF and HF-NL could result from comparing fibroblasts of different ages.