Words similar to txa

Example sentences for: txa

How can you use “txa” in a sentence? Here are some example sentences to help you improve your vocabulary:

Ibuprofen prevents the formation of TxA 2 , as well as platelet and leucocyte aggregation [ 12 21 ] . Fletcher et al.
On the other hand, PGI 2 decreases vascular smooth muscle cell proliferation and collagen and glycosaminoglycane synthesis, via activation of adenylyl cyclase and subsequent production of cAMP [ 17 ] . Betaprost, an analog of PGI 2 , decreases procollagen I and III mRNA expression in cardiac fibroblasts [ 18 ] . These effects may counteract the profibrotic effects seen with TXA 2 and it is possible that an alteration of a "normal" physiologic balance between PGI 2 and TXA 2 could increase tendency towards fibrogenesis.
The ratio of PGI 2 to TXA 2 metabolites was lower in IPF fibroblasts at baseline and with IL-1β stimulation.
We hypothesize that the lower PGI 2 :TXA 2 ratio seen in HF-IPF may be a phenotypic alteration that plays a role in the pathogenesis of IPF.
It is important to mention that our experiments were conducted at similar passage levels (passage 6 to 8) in both groups, since senescence of fibroblasts is associated with a shift from the biosynthesis of PGI 2 to TXA 2 [ 24 25 ] . It is possible that the difference seen in our study between HF-IPF and HF-NL could result from comparing fibroblasts of different ages.