Example sentences for: txa

How can you use “txa” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • TxA 2 is a product of arachidonic acid and a potent platelet aggregator, whose levels increase during endotoxic shock.

  • TXA 2 production tended to be greater in IPF than in normal fibroblasts at baseline; when stimulated with IL-1β this difference became statistically significant.

  • Because PGI 2 and TXA 2 have opposing effects in vivo , we calculated the ratio of their metabolites (6-keto-PGF 1α :TXB 2 ) and found a significantly lower ratio in HF-IPF at baseline (0.

  • The effects of PGs on cell proliferation and collagen production have been widely studied in different cell types [ 13 14 15 16 17 26 ] . TXA 2 has been studied extensively because of its apparent role in atherosclerosis, due to its prothrombotic and mitogenic activities on vascular smooth muscle cells [ 15 16 ] . These mitogenic effects are potentiated by growth factors [ 15 16 27 28 ] . In vascular smooth muscle cells TXA 2 stimulates synthesis of bFGF and increases the expression of the proto-oncogenes c-fos , c-myc , and egr-1 , which are associated with entry into the cell growth cycle [ 15 ] . In addition, TXA 2 increases proliferation of fibroblasts [ 13 ] and smooth muscle-like glomerular mesangial cells [ 14 ] .

  • The ratio of PGI 2 to TXA 2 metabolites was lower in IPF fibroblasts at baseline and with IL-1β stimulation.


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