Example sentences for: two-point

How can you use “two-point” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Due to the genetic homogeneity of the Finnish population [ 36 37 38 39 40 ] the probability of identifying genetic risk factors in a complex disease such as FIA may be substantially improved [ 37 38 40 ] . In the first stage a 10 cM genome scan was performed using the Weber screening set 8 [ 32 ] and the data analyzed using both two-point and multipoint ASP linkage analysis.

  • The largest two-point and multi-point LOD scores were obtained in the HLA region.

  • Two-point linkage in the presence of locus heterogeneity was assessed by the admixture test of Ott, using HOMOG [ 36 ] . We used a heterogeneity LOD (HLOD) of > 1.3 to indicate nominal evidence for linkage for all linkage analyses [ 37 ] .

  • The G3 and TNG maps were generated using the RHMAP 3.0 program package [ 14 ] . The RH2PT program was used initially to determine two-point lod scores and all the markers were divided into different linkage groups.

  • Several biostatisticians have suggested that general models provide power to distinguish linkage signals independent of the true underlying disease mode of inheritance, provided both dominant and recessive models are used [ 38 39 40 ] . As expected, the highest two-point and multipoint LOD scores were obtained in the HLA region, with a two-point HLOD of 3.1 and a multipoint HLOD of 5.0.


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