Example sentences for: two-fold

How can you use “two-fold” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Cellular response to chronic TLK286 exposure included a two-fold decrease in GSTP1-1 protein levels, confirming a GSTP1-1 mediated mechanism of activation [ 7 ] . Mouse embryo fibroblast cells from GSTP1-1 deficient animals elevated the expression of signal-regulated kinases ERK1/ERK2 and reduced the doubling time of cell proliferation [ 8 ] . That paper also found that a clone of HL60 cells resistant to TLK199, an inhibitor of GSTP1-1, has been shown to have elevated activities of c-Jun NH 2 -terminal kinase (JNK) and ERK1/ERK2.

  • Those probes whose signal intensities were increased at least two-fold are summarized in Table 1. As Table 1shows, for a number of transcripts substitution with MeC or MeU may potentially augment hybridization signals more so than even DAP.

  • Yesterday's White House response to Willey was primarily two-fold: a strong denial from President Clinton, and the release of a raft of friendly letters Willey sent to the White House after the date she alleges she was groped by Clinton.

  • 113 nM) and similar to the previously reported K d of 0.056 nM for the wild-type alpha-2 receptor for [ 3H]rauwolscine in NaPO 4 buffer [ 23 ] . Inhibition experiments with [ 3H]rauwolscine indicated that the affinity of norepinephrine for the mutated receptors was approximately two-fold higher (lower K d value) than for wild-type receptor (Figure 3).

  • Kidney and lymphoma cRNA samples containing either no modified NTPs or 1:1 DAP:A were hybridized in duplicate to Human Uniset I arrays; average kidney to lymphoma ratios were calculated and plotted (Figure 5) after removing signal outliers defined as a two-fold difference between replicates.


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