Words similar to trd
Example sentences for: trd
How can you use “trd” in a sentence? Here are some example sentences to help you improve your vocabulary:
Clonal mutant and wild-type MECP2 expressing fibroblast cell strains were successfully established from four Rett females with different mutations, one missense in the MBD, one missense in the TRD and two frameshift mutations leading to premature stop codons.
MeCP2's functional structure consists of an 84 amino acid methyl-binding domain (MBD) [ 11 ] and a 104 amino acid transcriptional repression domain (TRD) [ 12 ] . The MBD is able to bind to 5-methyl cytosine residues of a single CpG dinucleotide [ 11 ] . Under the current model, MeCP2 binds to DNA, then complexes with Sin3A through the TRD and recruits histone deacetylases (HDAC).