Words similar to trcp

Example sentences for: trcp

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Similarly, β-TRCP1 and 2, which target IκBα for degradation as homooligomers, form heterooligomers that each bind SCF core subunits, although no biochemical activity for this heterooligomeric complex was demonstrated [ 29 ] . Finally, Pop1p and Pop2p homooligomerize, at least when overexpressed [ 18 ] , indicating that both F-box proteins may also be present as homooligomers in individual SCF Pop1pand SCF Pop2p, respectively.
Similarly, dimerization of β-TRCP proteins is mediated by N-terminal "D-domains" lacking binding of SKP1 and other SCF core subunits [ 29 ] . According to our model, the F-box of Pop2p would be essential only for the Pop1p-independent activities of Pop2p, for which we provide tentative evidence by demonstrating the in vivo assembly of SCF Pop2pcomplexes (Fig.