Example sentences for: trans-silencing

How can you use “trans-silencing” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Test for acquired trans-silencing activity

  • Imprinting relay: Do trans-silenced E82 and L91 loci acquire trans-silencing ability?

  • Our data suggested that the C73 locus may have acquired its trans-silencing activity as part of an epigenetic transition from type E to type C silencing between the T1 and T3 generations.

  • The trans-silencers as well as their targets reside in single-copy, gene-rich regions that are only sparsely populated with repetitive or transposable elements, features that have been shown to mediate epigenetic activity in other cases [ 18 31 32 ] . Therefore trans-silencing of GFP-COP1 is probably not mediated by transgene flanking sequences [ 27 ] . In contrast, as with other genes cited above, trans-silencing ability is correlated with transgene locus structure, given that the C73 and C97 trans-silencers contain multiple T-DNAs while their targets, E82 and L91, are essentially dimeric and monomeric, respectively.

  • Here, combining a master locus (C73) with a non-allelic singlet locus possessing 100% sequence identity (L91) resulted in immediate trans-silencing, as seen by a reduction of GFP-COP1 expression and block of cosuppression, which was stably maintained in the presence or absence of the master locus.


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