Words similar to tnfα

Example sentences for: tnfα

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These data demonstrate that TNFα is a potent inducer of both Rel A and p50 whereas RSV primarily induces the Rel A subunit of NF-κB.
However, the effects of DEX on NF-κB binding induced by TNFα did not correlate with its effects on chemokine expression, suggesting in TNFα activation of chemokine gene expression DEX targets another mechanism of chemokine induction not involving NF-κB.
Other mechanisms that may participate in the RU 486-induced inhibition of hepatic apoptosis include the fact that this compound blocks the inhibitory effect of glucocorticoids on suppressors of cytokine signalling in the liver [ 8 ] . This family of proteins is induced by growth hormones and cytokines, and is strongly repressed in vivo by glucocorticoids [ 8 ] . Up-regulation of these proteins by RU 486 [ 8 ] , coupled with significant increase in hepatic TNFα level found in animals treated with RU 486 [ 12 ] , may contribute to the inhibition of apoptosis observed in our study (Fig 1B).
The RSV induction kinetics differed dramatically from the induction kinetics for TNFα in the same experiment.
However, treatment with C2 ceramide did activate the JNK pathway similar to that observed with TNFα treatment (Fig.