Example sentences for: tnfβ

How can you use “tnfβ” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Notably, of the 16 IL-2-induced genes, we had already been identified 4 previously as IL-2 targets using differential colony hybridization (CR3, CR6, CR7, CR8) [ 29 ] , while the 3 other known IL-2 stimulated target genes included TNFβ, the IL-4R, and the anti-apoptotic gene, Bcl2.

  • In the case of the surrogates for both HCV-mRNA and TNFβ, it is clear that the large diversity and size of the original library was, in fact, critical to their successful isolation since libraries of <20 amino acids would not have contained either the KcB7 peptide or the HCV-specific surrogates.

  • The cross reactive phages from the eluted phage were then subtracted by panning sequentially against human TNFR1, TNFα and TNFβ as a way to obtain peptides specific to the original target.

  • All of the peptides were competed by both TNFα and TNFβ implying they recognized a hotspot that mapped either within or at least overlapping the ligand-binding domain of TNFR2.

  • No appreciable sequence homology was seen between either of the natural ligands, TNFα or TNFβ, and KcF12 although the spacing of cysteine loop was close to that seen in the cysteine rich domains of TNFR2 [ 29 ] . At present, it is not known whether these structural elements play a role in binding of the peptides to TNFR2 and it may be that the peptides mimic rather than recapitulate the contact domains of the natural ligands.


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