Words similar to tnf-α
Example sentences for: tnf-α
How can you use “tnf-α” in a sentence? Here are some example sentences to help you improve your vocabulary:
Moreover, anti-TNF-α treatment resulted in a modest inhibition of murine IL-1β production in the diseased joint, which is consistent with previous findings that anti-TNF-α antibody inhibits the generation of IL-1 in collagen-induced arthritis and IL-1, IL-6, and IL-8 in rheumatoid synovial cultures [ 26 27 ] . Our study provides preclinical evidence supporting the use of anti-TNF-α mAb in ameliorating arthritic pathology.
Interestingly, the 4 hour time point corresponded to the highest level of TNF-α mRNA expression shown in Fig.
In this experiment, IL-10 induction in the endothelium efficiently blocked TNF-α induced MAdCAM-1 expression and α4β7-dependent lymphocyte adhesion on SVEC endothelial cells.
Thus in the aging and HIV +scenario, it is apparent that the CD8 +T cells show an enhanced capacity for both TNF-α production and IFN-γ production.
We have described in vitro that exogenous IL-10 can block the expression of MAdCAM-1 in response to TNF-α, and attenuates lymphocyte adhesion to lymphatic node derived endothelium under cytokine stimulating conditions via NF-kB inhibition [ 5 ] . The purpose of the current study was to show that induction of endothelial expression of IL-10 through an IL-10 expression vector attenuates MAdCAM-1 expression in response to TNF-α and optimistically suggests the possibility of targeted Th2-cytokine gene therapy in IBD.
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