Example sentences for: tm-helical

How can you use “tm-helical” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, it is unlikely that polytopic membrane domains in the 12-TM Pfam-A families have a structure like that of ABC transporters; as there is no obvious sequence similarity within the sequence containing the 12 TM-helices, it is unlikely to form two 6-TM-helical bundles.

  • By studying the families in C. elegans, we found that it has an exceptional number of 7-TM-helical membrane domains, most of which are annotated as chemoreceptors.

  • Therefore, glycine, proline and tyrosine are relatively conserved residues in TM-helical regions, and isoleucine, valine, methionine and threonine have relatively high mutability.

  • It contains 12 TM-helices in a homodimer of two 6-TM-helical bundles, which form a central chamber to translocate substrates.

  • In the analysis of amino-acid positions, glycine, proline and tyrosine were found to be the most conserved residues in TM-helical regions, whereas isoleucine, valine, methionine and threonine were identified as the least conserved residues, relative to average occurrence.


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