Words similar to tlr
Example sentences for: tlr
How can you use “tlr” in a sentence? Here are some example sentences to help you improve your vocabulary:
Our present knowledge of Tlr4 structural variation in mice may permit an answer to this question, insofar as the mutations might easily be recreated, and measurements of signal-transducing activity through the modified receptors carried out in immortalized C3H/HeJ macrophages [ 13].
Genetic variation at the mouse Tlr4locus
Both approaches reveal that the extracellular domain of Tlr4 is highly variable compared with the transmembrane domain and proximal cytoplasmic domain of the protein.
The function of Tlr4 as the LPS signal transducer became clear when mapping [ 10] and sequencing [ 11] data revealed Tlr4 as the only gene in a critical 2.6 megabase (Mb) region and, furthermore, showed that two strains of LPS-resistant mice are homozygous for mutations of Tlr4 that are absent in closely related LPS-sensitive strains.
We recently identified the Lps locus through positional cloning [ 10] and showed that the LPS-resistance phenotype was caused by defects in the Toll-like receptor 4 gene ( Tlr4 ) [ 11].
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