Example sentences for: tlr

How can you use “tlr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Our present knowledge of Tlr4 structural variation in mice may permit an answer to this question, insofar as the mutations might easily be recreated, and measurements of signal-transducing activity through the modified receptors carried out in immortalized C3H/HeJ macrophages [ 13].

  • Genetic variation at the mouse Tlr4locus

  • Both approaches reveal that the extracellular domain of Tlr4 is highly variable compared with the transmembrane domain and proximal cytoplasmic domain of the protein.

  • The function of Tlr4 as the LPS signal transducer became clear when mapping [ 10] and sequencing [ 11] data revealed Tlr4 as the only gene in a critical 2.6 megabase (Mb) region and, furthermore, showed that two strains of LPS-resistant mice are homozygous for mutations of Tlr4 that are absent in closely related LPS-sensitive strains.

  • We recently identified the Lps locus through positional cloning [ 10] and showed that the LPS-resistance phenotype was caused by defects in the Toll-like receptor 4 gene ( Tlr4 ) [ 11].


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