Words similar to tlr

Example sentences for: tlr

How can you use “tlr” in a sentence? Here are some example sentences to help you improve your vocabulary:

The cytoplasmic domain of Tlr4 is far more stringently conserved than the extracellular domain.
This would seem still more likely at present, given the paucity of other candidate genes in the immediate vicinity of Tlr4 [ 10].
The ancestry of different Tlr4 alleles can be traced by haplotype analysis, as many deviations from the reference allele occur in conjunction with one another.
The pathway by which LPS activates host innate immune defenses has been illuminated by the positional cloning of Lps and establishment of its identity with Tlr4 [ 11], a mammalian representative of an ancient family of receptors [ 16] that serve both developmental and defensive functions.
Subsequently, overexpression of the wild-type Tlr4 protein was found to enhance LPS signal transduction in wild-type macrophages, lowering the effective concentration (EC 50 ) for LPS by a factor of 30, whereas overexpression of the Tlr4 Lps-disoform represented in C3H/HeJ mice almost completely suppresses signaling [ 12].