Words similar to thromboxane

Example sentences for: thromboxane

How can you use “thromboxane” in a sentence? Here are some example sentences to help you improve your vocabulary:

Prostanoids are important regulators of fibroblast function [ 5 6 7 8 9 ] . Prostaglandin (PG)E 2 is thought to have antifibrotic properties in vitro , but also can have proinflammatory effects both in vivo and in vitro [ 10 11 12 ] . Thromboxane (TX)A 2 increases proliferation, and DNA and RNA synthesis in several cell types, including fibroblasts and smooth muscle like glomerular mesangial cells [ 13 14 15 16 ] . Conversely, prostacyclin (PGI 2 ) decreases smooth muscle cell proliferation and collagen synthesis [ 17 18 ] .
COX = cyclooxygenase; HF = human fibroblasts; NL = normal lungs; IPF = idiopathic pulmonary fibrosis; IFN = interferon; IL = interleukin; PG = prostaglandin; TX = thromboxane; PGI 2 = prostacyclin.
We have found that fibroblasts cultured from normal and IPF human lungs have a significant and similar induction of the COX-2 enzyme when stimulated with IL-1β, but that IPF fibroblasts produced more thromboxane and had a significantly lower prostacyclin:thromboxane ratio.
Ibuprofen is a reversible, short-acting cyclooxygenase inhibitor, which particularly blocks the synthesis of thromboxane.
There was a greater than 50% reduction in PG D 2 production in clone 11 compared with the vector only control and a similar decrease in levels of PGs F 2α , 6keto-F 1α and thromboxane B 2 in this clone (Fig 7A).