Example sentences for: thrombin

How can you use “thrombin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These include increased platelet activation, increased thrombin generation, and more recently, elevated levels of circulating tissue factor [ 14 ] . Over the past decade, mutations in a number of genes have been identified as the cause of thrombophilia in a large number of patients from different populations around the globe.

  • With single mutation at position Glu351, we improved reactivity of PAI-1 to thrombin and plasmin without significantly affecting its specificity to tPA.

  • PN-1 has four known target proteases: urokinase plasminogen activator (uPA), tissue type plasminogen activator (tPA), thrombin and trypsin [ 17 ] . Evidence exists for a role of both trypsin [ 18 19 ] and uPA [ 20 21 ] in migratory processes.

  • [ 15 27 ] The specificity of the two mutants toward thrombin and plasmin implicates that Glu351 of PAI-1 is involved in its specificity toward thrombin and plasmin.

  • Plasmin and thrombin with moderate reactivity toward PAI-1 have relatively short variable regions which contain only two to three positively charged residues.


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