Words similar to thrombin
Example sentences for: thrombin
How can you use “thrombin” in a sentence? Here are some example sentences to help you improve your vocabulary:
Thrombin, or plasmin activity without PAI-1 was taken as 100%.
The process of membrane vesiculation and MP-release in platelets has been shown to require a calpain-dependent dissociation of membrane proteins from the submembrane cytoskeleton and most likely involves intracellular signaling by platelet protein kinases [ 10 ] . Besides platelets stimulated by various agonists such as thrombin with collagen or the complement complex C5b-9 [ 7 11 ] , a release of PS-containing membrane MP was demonstrated in other cell types such as endotoxin-stimulated monocytes [ 12 ] , polymorphonuclear leucocytes stimulated with the chemotactic peptide FMLP [ 13 ] or apoptotic T-lymphocytes [ 14 ] . The normal restriction of PS to the inner surface of the plasma membrane becomes perturbed in apoptotic cells [ 15 16 ] . When exposed, PS is a determinant for phagocyte recognition of cells to be cleared.
As described previously [ 6 ] , a pGEX2 vector, encoding the actin-binding domain, residues 2-269 of chicken smooth muscle α-actinin, fused with the carboxy terminus of glutathione S-transferase (GST) with an engineered thrombin cleavage site, was kindly provided by Dr DR Critchley of the University of Leicester, UK.
Recombinant Ppt1p expressed as a GST-fusion protein, then affinity purified and released from GST by thrombin cleavage yielded a single band of the expected molecular weight, 58 kDa (Fig.
These include increased platelet activation, increased thrombin generation, and more recently, elevated levels of circulating tissue factor [ 14 ] . Over the past decade, mutations in a number of genes have been identified as the cause of thrombophilia in a large number of patients from different populations around the globe.
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