Example sentences for: thrombin

How can you use “thrombin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • PS-exposing MP in blood appear to act as the catalytic surface for assembly of the prothrombinase complex [ 7 ] . Although circulating MP of various cellular origin in patient with sepsis were reported to be procoagulant through multiple mechanisms [ 8 9 ] , in healthy individuals they may have an anticoagulant function by promoting the generation of low amounts of thrombin that activate protein C [ 2 ] .

  • [ 15 27 ] The specificity of the two mutants toward thrombin and plasmin implicates that Glu351 of PAI-1 is involved in its specificity toward thrombin and plasmin.

  • Substitution of Glu351 also altered the specificity toward non-cognate proteases: plasmin and thrombin.

  • PN-1 has four known target proteases: urokinase plasminogen activator (uPA), tissue type plasminogen activator (tPA), thrombin and trypsin [ 17 ] . Evidence exists for a role of both trypsin [ 18 19 ] and uPA [ 20 21 ] in migratory processes.

  • Mutations at Glu351 may decrease the original repulsive interactions with variable region of thrombin, which may slow the rate of thrombin inhibition, or results in favorable interactions that may not exist when wtPAI-1 react with thrombin.


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