Example sentences for: thrombin

How can you use “thrombin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Glu at 351 may provide steric hindrance that slows the rate of thrombin or plasmin inhibition.

  • With single mutation at position Glu351, we improved reactivity of PAI-1 to thrombin and plasmin without significantly affecting its specificity to tPA.

  • When excess equal amount of thrombin was incubated with equal amount of PAI-1s in term of inhibitory activity against uPA, mutant inhibitors were neutralized faster by thrombin than wtPAI-1, and vitronectin also facilitated the neutralization of Glu351Ala or Glu351Arg by thrombin, just similar to the wtPAI-1 (Fig.

  • This indicates that Glu351 is not essential for the interaction with tPA, but it is an very important determinant for the optimal interaction with uPA, thrombin and plasmin.

  • More importantly, Glu351 of PAI-1 is a specificity determinant for uPA, thrombin and plasmin, but not for tPA.


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