Example sentences for: thiolates

How can you use “thiolates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Furthermore, the reactivity of a thiol depends upon its pKa, as thiolates are orders of magnitude more nucleophilic than thiols [ 54].

  • As mentioned above, proteins—in particular, the thiols of cysteines—are the major targets of H 2 O 2 . The reaction of cysteinyl thiolates with H 2 O 2 can lead to the formation of different modifications, such as sulfenic acid (–SOH), sulfinic acid (–SO 2 H), and sulfonic acid (–SO3H), as well as disulfide bond formation (–S–S–) and glutathione conjugation (–S–GSH) (Jacob et al.

  • Recent progress in this field points to a common chemistry in the reaction of H 2 O 2 with thiolates through the initial formation of sulfenic acid.

  • The pKa of the thiolates clearly plays an important role, as thiolates are more reactive than their protonated counterparts.


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