Example sentences for: thiols

How can you use “thiols” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For these proteins, the cysteine residues, which form intramolecular disulfide bonds, are in a reduced state when coordinated to a zinc ion (Zn 2+ ), and zinc is released upon oxidation of the thiols.

  • Perhaps Zn binding provides some additional control over the reactivity of the cysteine thiols, or perhaps the loss of the zinc facilitates conformational changes.

  • The tripeptide glutathione and the thiol reductants glutaredoxin and thioredoxin are key to the restoration of thiols to their reduced state (SH) (Fernandes and Holmgren 2004).

  • However, lipid hydroperoxide-induced apoptosis is accompanied by an alteration in the intracellular redox balance leading to a depletion of intracellular thiols and subsequent activation of caspases and PARP cleavage [ 33 ] , responses that would be attenuated by hydrophilic antioxidants.

  • As mentioned above, proteins—in particular, the thiols of cysteines—are the major targets of H 2 O 2 . The reaction of cysteinyl thiolates with H 2 O 2 can lead to the formation of different modifications, such as sulfenic acid (–SOH), sulfinic acid (–SO 2 H), and sulfonic acid (–SO3H), as well as disulfide bond formation (–S–S–) and glutathione conjugation (–S–GSH) (Jacob et al.


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