Example sentences for: thiols

How can you use “thiols” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Another component to the oxidative stress response is the reduction of oxidized thiols that arises through one of the mechanisms described below.

  • Perhaps Zn binding provides some additional control over the reactivity of the cysteine thiols, or perhaps the loss of the zinc facilitates conformational changes.

  • As mentioned above, proteins—in particular, the thiols of cysteines—are the major targets of H 2 O 2 . The reaction of cysteinyl thiolates with H 2 O 2 can lead to the formation of different modifications, such as sulfenic acid (–SOH), sulfinic acid (–SO 2 H), and sulfonic acid (–SO3H), as well as disulfide bond formation (–S–S–) and glutathione conjugation (–S–GSH) (Jacob et al.

  • Furthermore, the reactivity of a thiol depends upon its pKa, as thiolates are orders of magnitude more nucleophilic than thiols [ 54].

  • For these proteins, the cysteine residues, which form intramolecular disulfide bonds, are in a reduced state when coordinated to a zinc ion (Zn 2+ ), and zinc is released upon oxidation of the thiols.


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