Words similar to thiols
Example sentences for: thiols
How can you use “thiols” in a sentence? Here are some example sentences to help you improve your vocabulary:
Another component to the oxidative stress response is the reduction of oxidized thiols that arises through one of the mechanisms described below.
Perhaps Zn binding provides some additional control over the reactivity of the cysteine thiols, or perhaps the loss of the zinc facilitates conformational changes.
As mentioned above, proteins—in particular, the thiols of cysteines—are the major targets of H 2 O 2 . The reaction of cysteinyl thiolates with H 2 O 2 can lead to the formation of different modifications, such as sulfenic acid (–SOH), sulfinic acid (–SO 2 H), and sulfonic acid (–SO3H), as well as disulfide bond formation (–S–S–) and glutathione conjugation (–S–GSH) (Jacob et al.
Furthermore, the reactivity of a thiol depends upon its pKa, as thiolates are orders of magnitude more nucleophilic than thiols [ 54].
For these proteins, the cysteine residues, which form intramolecular disulfide bonds, are in a reduced state when coordinated to a zinc ion (Zn 2+ ), and zinc is released upon oxidation of the thiols.