Example sentences for: thickened

How can you use “thickened” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Lee comes on to virtually every beautiful woman he meets and has an amazing amount of success for someone so otherwise unsuccessful and so thickened with dissipation.

  • The margin of the operculum is thickened but does not yet flare.

  • The nerve fiber layer, composed of retinal ganglion cell axons was not evident even adjacent to the scleral foramen where it is normally substantially thickened due to axon convergence on the optic nerve.

  • Years of sitcom work haven't softened Goodman, whose Larry is sour, unlovable, thickened by indifference.

  • The first evidence that chemokines are associated with wound healing in vivo was reported in 1990 using the chemokine cCAF (chicken Chemotactic and Angiogenic Factor; the product of the 9E3 gene), a CXC chemokine that is now known to be the ortologue for human IL-8 [ 9 ] . cCAF is expressed to high levels very shortly after wounding and during the first 24-48 hours after injury, and remains elevated for at least 16 days after wounding [ 6 10 ] . It is primarily expressed by the fibroblasts of the granulation tissue, especially where interstitial collagen (Coll) is abundant, but the levels are also high in the endothelial cells of the microvessels, in the healing epidermis and in the connective tissue beneath the skin [ 6 11 ] . In the chicken chorioallantoic membrane (CAM) assay, low concentration of cCAF results in chemotaxis of monocyte/macrophages and lymphocytes and the formation of a granulation-like tissue beneath the chemokine-containing pellet [ 3 ] . After four days of exposure to this chemokine, the ectoderm of the CAMs becomes thickened and the amount of fibrillar collagen in the tissue is markedly increased, strongly suggesting that cCAF is able to initiate some of the primary events that lead to granulation tissue formation [ 3 ] .


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