Words similar to tetraploid

Example sentences for: tetraploid

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However, pioneering work by Nagy et al has shown that embryos and mice can be derived directly from R1 ES cells by aggregating them with tetraploid embryos [ 7 8 ] . This suggests that controlled expression of transgenes encoding possible gain-of-function and developmental-lethal alleles could be achieved by generating embryos and/or mice from ES cells containing transgenes inserted into the hprt locus.
Tetraploid aggregation and β-galactosidase staining
We next addressed whether embryos could be generated solely from F3 Hprt negative ES cells by aggregating these cells with tetraploid CD-1 embryos and allowing them to develop in utero until day 13 of gestation (El 3).
In this report, we describe the generation of a new Hprt negative ES cell line that is compatible with the tetraploid aggregation procedure.
Mouse embryos derived solely from ES cells were generated by tetraploid aggregation as described previously [ 18, 19, 20].