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Example sentences for: surfaces
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This result is in contrast with our previous study, which showed that greater than 95% of biotinylated Ad5.CMV-LacZ, prepared under the same conditions, can be readily captured on streptavidin-coated microbeads [ 10 ] . Thus, the relatively low immobilization efficiency of biotinylated Ad5.CMV-LacZ on the surface of streptavidin-coated wells is not attributable to the absence of accessible biotin moieties on the surfaces of a fraction of viral particles or the presence of unreacted biotinylation reagent in the biotinylated Ad5.CMV-LacZ preparations.
The alkyl backbone of the transported glycerol is adjacent to the hydrophobic surface and the hydroxyl groups form hydrogen bonds with the hydrophilic surfaces [ 23, 24].
In this strategy, adenoviral particles are immobilized, tightly and stably, on solid surfaces (virus-coated solid surfaces), while maintaining their natural properties, including infectivity.
An alternative is that these lateral surfaces mediate association of protofilaments with each other, to form protofilament pairs or small sheets.
It has been proposed that the GAG-binding property of PEDF provides the molecular basis for its association with extracellular matrices and may serve to localize PEDF activity in the retina and CNS [ 14 19 ] . However, the present results point to direct effects these polysaccharides might have on the biochemical interactions between PEDF and PEDF receptors on the surfaces of cells that respond to this neurotrophic factor.