Example sentences for: superoxide

How can you use “superoxide” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We have also demonstrated that mesalamine (5-aminosalicylic acid), used as a frontline treatment for inflammatory bowel disease, could prevent apoptotic epithelial cell death in response to peroxynitrite [ 14 ] . Peroxynitrite is a potent oxidant; formed from two free radicals - nitric oxide and superoxide - that catalyzes the nitration of tyrosine residues.

  • Superoxide dismutase (SOD) activity of tissue homogenates was determined using a microplate adaptation of the ferricytochrome C reduction assay of Flohé and Ötting [ 26 ] . In this method, the reduction of cytochrome C by superoxide radicals is monitored at 550 nm utilizing the xanthine-xanthine oxidase system as the source for superoxide.

  • A similar vascular hyper-responsiveness has been noted in caveolin-1 knock-out mice [ 25 26 ] raising the possibility that the accumulation of Gb 3 results in over-activity of uncoupled endothelial nitric oxide synthase within endothelial cell caveolae generating superoxide and other reactive oxygen species [ 27 ] . The latter may have a vasodilatatory effect [ 28 ] . Predominance of vascular abnormalities in the vertebro-basilar system in Fabry disease suggests fundamental biologic differences between the anterior and the posterior circulation.

  • Free-radicals ( e.g. , superoxide, hydroxyl radicals, nitric oxide and peroxynitrite) have long been thought to be a key element in the cellular dysfunction and death that are central to the pathogenesis of many aspects of diabetes.


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