Words similar to superfamily
Example sentences for: superfamily
How can you use “superfamily” in a sentence? Here are some example sentences to help you improve your vocabulary:
The human FHIT gene, located at the chromosome 3 fragile site FRA3B, is inactivated early in the development of many tumors [ 1 ] . Murine Fhit is also located at a fragile site [ 2 3 ] and mice heterozygous for disruption of Fhit , given low intragastric doses of the mutagen N-nitrosomethylbenzylamine, develop stomach and sebaceous tumors [ 4 ] that can be prevented by viral Fhit expression [ 5 ] . Fhit, a dimer of 147 amino acid subunits, is a member of the histidine triad (HIT) superfamily of nucleotide hydrolases and transferases [ 6 7 ] . Members of the Hint branch of the HIT superfamily are found in all forms of life [ 8 ] . The S. cerevisiae Hint homolog, Hnt1, and rabbit Hint possess adenosine monophosphoramidase activity that functions in yeast to positively regulate function of Kin28, Ccl1 and Tfb3, which constitute the kinase component of general transcription factor TFIIH [ 9 ] . A new Hint related protein, Aprataxin, is mutated in individuals with ataxia with oculomotor apraxia [ 10 11 ] and has a yeast homolog termed Hnt3 [ 9 ] . Members of the Fhit branch of the HIT superfamily have been found in fungi [ 12 13 ] , animals [ 2 14 15 ] and plants [ 7 ] and hydrolyze diadenosine tetraphosphate, diadenosine triphosphate and other 5'-5"'-dinucleoside polyphosphates.
Here we use sequence-profile analysis and comparative genomics to show that the β-barrel domain of PRC-H defines a novel, widespread superfamily of β-barrel domains that is represented in several bacterial, plant and archaeal genomes.
These results suggest that the function of TGF-β superfamily may be a prerequisite for the arterial dilatation and that endothelial cells and the smooth muscle cells may be responsible for the forth-going vessel enlargement.
MM2478 is a rare instance of an NlpC/P60 superfamily member occurring in the archaeal lineage.
The kinesin superfamily in humans and mice is comprised of at least 45 members, designated with the prefix KIF [ 26 ] . Based on this naming system we have assigned the name KIF27 to this new family member with the suffixes A, B and C to designate the splice variants described above (figure 3B).
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