Example sentences for: superfamily

How can you use “superfamily” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Its place is occupied by its single substrate, L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine, whose carboxyl sidechain interacts with the conserved basic residue similarly to the OG-carboxylate in the other enzymes of this superfamily [ 9, 10].

  • Sequence conservation is high within individual families of the 2OG-Fe(II) dioxygenase superfamily, with specific extensions typical of each family, but low between different families (Figure 1).

  • We use sequence profile analysis [ 13, 14] to show that the DNA-repair protein AlkB, the extracellular matrix protein leprecan and the disease-resistance-related protein EGL-9 define new families of the 2OG-Fe(II) dioxygenase superfamily.

  • Distinct nAChR subtypes exist that can be stimulated by the neurotransmitter acetylcholine, the natural product nicotine, or by synthetic compounds [ 1 ] . nAChR is the prototype for a protein superfamily that includes the receptors for the excitatory amino acids glutamate and aspartate, the inhibitory amino-acids gamma-aminobutyric acid (GABA) and glycine, as well as the serotonin 5-HT 3 receptor [ 1 ] . Like most ligand-gated ion channels, nAChRs are homo- or hetero-pentameric, each monomer belonging to a pull of 8 alpha- or 3 beta-subunits (alpha 2-9 , beta 2-4 ). While each subunit has four transmembrane domains, the agonist binding sites are located at the subunit interfaces [ 2 ] . Both natural and synthetic ligands can display varied affinity for different receptor subtypes.

  • The second superfamily typified by the ERF proteins is predominantly found in bacteriophages and is also present on all circular plasmids from Borrelia, suggesting a role in the recombination of these plasmids.


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