Words similar to superfamily
Example sentences for: superfamily
How can you use “superfamily” in a sentence? Here are some example sentences to help you improve your vocabulary:
E174 in ACR3 and S218 in ACR4 are required for catalytic function [ 12 ] . Substitution of H59 in ACR1 converted CD39 into an ADPase in a quaternary structure dependent manner [ 13 ] . Mutation of W187A in ACR3 affected CD39 folding and translocation, while mutation of W459A in ACR5 increased ATPase activity but diminished ADPase activity [ 14 ] . Mutations of D62 and G64 of ACR1 and D219 and G221 of ACR4 demonstrated that the nucleotide phosphate binding domains of NTPDases are similar to those present in the actin/heat shock protein/sugar kinase superfamily [ 15 ] . These results suggest that the conserved residues of the ACR1 to 5 regions are involved in the catalytic mechanism of CD39.
Experimental studies have shown that the strand transfer reaction mediated by RecT and its binding to dsDNA are sensitive to Mg +2concentrations and it was proposed that the levels of free Mg +2could regulate RecT activity [ 4 ] . Similarly, Redβ has been shown to promote single strand annealing in a Mg +2-dependent manner [ 20 ] . In this context, the conservation of the two C-terminal acidic residues in the majority of members of this superfamily suggests that these might be involved in the coordination of Mg +2and implies that the metal ion-dependent conformational switching is likely to be a generic feature of this family.
Here, we have used the fold and superfamily assignments from the SCOP [ 14] and Superfamily databases [ 15] and the family classifications from InterPro [ 16, 17].
HSP20 is a member of the heat shock protein superfamily and is known to provide resistance to heat treatment in cells [ 13 ] . Recently we found that heat pretreatment (4 hours at 44.
Using sensitive sequence profile comparison methods, we show that the CyaB-like adenylyl cyclases are homologs of the soluble mammalian thiamine triphosphatases [ 17 ] , and they define a novel superfamily of enzymes that utilize ATP and other organic phosphates.
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