Example sentences for: subcellular

How can you use “subcellular” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • It would be important not only to assess the immunogenic potential of subcellular particles and proteolytic fragments released during cell death, but also to continue investigating possible defects leading to aberrant apoptosis or phagocyte function and/or aberrant antigen expression in systemic autoimmune diseases.

  • As a comparison, a non-palmitoylated mutant of α q , in which cysteines 9 and 10 have been substituted with serines, is found predominantly in the soluble fraction (Figure 2E, lanes 7 and 8), as described previously [ 13 ] . Surprisingly, in comparison to α i2 , sα i2 was always detected in fewer cells, by immunofluorescence analysis, and showed lower levels of protein expression, by western blot analysis of subcellular fractions (Figure 2E) or whole cell lysates (not shown).

  • In addition to the key roles in E3 ligase activity, RING finger domains have also been shown to be important for regulating subcellular localization of E3s and/or their substrates in a number of cases [ 53 54 55 56 ] . Studies have shown the MDM2 RING finger domain is required to promote nuclear export of p53 and this activity of MDM2 RING finger seems to be coupled with its ability to promote ubiquitination of p53 [ 53 54 55 ] . Rbx1/ROC1, the small RING finger subunit of the SCF E3 complexes, promotes the nuclear accumulation of Cul1, another subunit of the SCF complexes [ 56 ] . These studies have suggested a correlation between the ubiquitination activities of RING fingers and their roles in regulating subcellular localization of the E3 ligases which they are part of.

  • Atorvastatin Activates sAPPα Shedding at a Subcellular Site Upstream of Endocytosis from the Plasma Membrane

  • Due to the novelty of the mammalian homolog of Seven in Absentia (Siah), little information is available regarding its tissue distribution or subcellular localization in mammalian cells.


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