Example sentences for: stimulates

How can you use “stimulates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The expression of oncogenes such as ras in untransformed cells stimulates transcription of the p14 Arfgene [ 2].

  • Capsaicin's use in the treatment of chronic pain is due to an analgesic effect that is explained by capsaicin's action of depletion of stores of substance P from primary sensory neurons as a consequence of the reduced production of prostaglandin [ 39 60 ] . Capsaicin's antiphlogistic activity is due to the "counter-irritant effect"; which means that a local irritant effect exerts an additional more remote antiinflammatory effect [ 60 ] . This is explained by a liberation of corticoids under the influence of certain cutivisceral reflexes [ 60 ] . The counter-irritant effect on the gastric mucosa also occurs because capsaicin stimulates production of the cytoprotective prostaglandin E 2 [ 60 ] . Capsaicin produces analgesic and antiinflammatory effects because it inhibits both 5-lipoxygenase and cycoloxygenase [ 39 ] . A 10 g human ingestion of red pepper stimulated carbohydrate oxidation [ 62 ] . This may explain why the Chocó Indians used it to give their hunting dogs more "energy" [ 25 ] .

  • It has been previously shown that PGE2 not only directly dilates renal arteries [ 9 10 11 ] but also attenuates the AngII-induced increase in renal vascular resistance [ 12 ] through inhibition of AngII-elicited intracellular Ca ++increase in vascular smooth muscle cells of preglomerular vasculature [ 13 ] . Based on the fact that PGE2 stimulates cAMP generation in freshly isolated preglomerular renal arterioles [ 14 ] , the cAMP-stimulating EP2 or EP4 receptor has been thought to mediate these effects of PGE2 on renal resistance vessels.

  • In choroid plexus, the 5-HT 2C receptor stimulates PI turnover, increases cGMP formation and activates Cl -channels.

  • Conversely, leptin stimulates cytokine activation and immune-cell proliferation, an effect that predisposes to inflammatory conditions [4].


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