Example sentences for: stimulates

How can you use “stimulates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Whether TGF-β1 directly or indirectly stimulates proliferation of synovium is unclear, but this pathology apparently is mediated through an IL-1β-independent mechanism.

  • NEDD8 modification stimulates SCF-dependent substrate ubiquitylation in vitro [ 2, 3, 4], and mutant CUL1 resistant to NEDD8 modification is defective in vivo [ 5].

  • It has been previously shown that PGE2 not only directly dilates renal arteries [ 9 10 11 ] but also attenuates the AngII-induced increase in renal vascular resistance [ 12 ] through inhibition of AngII-elicited intracellular Ca ++increase in vascular smooth muscle cells of preglomerular vasculature [ 13 ] . Based on the fact that PGE2 stimulates cAMP generation in freshly isolated preglomerular renal arterioles [ 14 ] , the cAMP-stimulating EP2 or EP4 receptor has been thought to mediate these effects of PGE2 on renal resistance vessels.

  • Some of the fibroblasts differentiate into myofibroblasts, which contract to close the wound [ 4 14 15 ] . Myofibroblasts are fibrogenic, showing elevated expression of interstitial collagens, laminin, FN and TN, and inhibitors of matrix metalloproteinases such as TIMP-1 [ 15 16 17 18 19 ] . Because cCAF is expressed highly in the granulation tissue of wounds in areas where ECM is abundant [ 3 6 11 ] , and it stimulates fibroblasts to differentiate into myofibroblasts [ 4 ] , we investigated whether this chemokine stimulates the production of the four major ECM molecules mentioned above, interstitial Colls I and III, TN and cellular FN.

  • The Threat stimulates viewers to ask the question the ad dare not raise directly: Is Clinton soft on drugs--and on moral issues in general?


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