Words similar to steric
Example sentences for: steric
How can you use “steric” in a sentence? Here are some example sentences to help you improve your vocabulary:
For instance, steric hindrance between the binding of the transcription factor Cro to its operator (Cro- OR1 ) and RNA polymerase (RNAP) to the promoter PR (RNAP- PR ) is represented by a double-headed 'inhibition' arrow linking the respective binding-reaction arrows.
The RNAseH active site must be in very close proximity to the polymerase site and be oriented in such a manner that it can access heteroduplexes within ∼ 18 base pairs of the 3' end of the growing DNA chain, and hence steric occlusion seems to be unlikely.
On the other hand, the very high Van der Waals repulsions calculated Table 1(bottom) for alpha4-beta4 and alpha7-alpha7 are a clear indication of a steric clash (Figure 5D): the ligand fits next to Ala 135 of beta2, but cannot accommodate Leu 135 of beta4.
For a steric interaction between nearest neighbors, the stoichiometry would seem to be limited to a factor of 4-5.
However, in the complex with RAR-α, this ketone oxygen shares an hydrogen atom with the hydroxyl group of serine 234, and forms a stabilizing hydrogen bond, while a steric clash occurs in the other two RAR isoforms, where residue 234 is an alanine.
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