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Example sentences for: sspnn
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The sequence environment of all donor- and acceptor sites was analysed using Splice Site Prediction by Neural Network (SSPNN, URL address: http://www.fruitfly.org/seq_tools/splice.html).
The SSPNN program gave the exons that can become skipped a significantly lower score (0.
These include 1) the strength of the 3' and 5' splice sites, which can be calculated using the consensus values that were determined by Shapiro and Senepathy [ 5 ] or by the Splice Site Prediction program by Neural Networks (SSPNN, http://www.fruitfly.org/seq_tools/splice.html) which takes more known sequences into account, 2) the branch point sequences and 3) certain sequences such as exonic splicing enhancers (ESE) that can activate the use of a weak 3' splice site or elements such as exonic splicing silencer elements (ESS) that inhibit splicing [ 1 ] . In addition to these cis -acting elements, exon length [ 6 ] and secondary structure have also been mentioned to play a role in splicing [ 7 ] .
Calculations were performed using the S plice S ite P rediction by N eural N etwork (SSPNN, http://www.fruitfly.org/seq_tools/splice.html) program (Table 1).