Example sentences for: spliceosome

How can you use “spliceosome” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Splicing is carried out by the spliceosome, a large complex consisting of proteins and small nuclear RNAs (snRNAs) [ 1 2 3 ] . RNA splicing is dependent upon the identity of nucleotide sequences at the exon/intron boundaries.

  • An information analysis was done of the 50 nt upstream and downstream of the different rRNA spliceosomal intron sites to determine the total amount of exonic information (in "bits") that is available to the spliceosome for splicing.

  • Our studies on nmt55 and those of p54 nrbhave characterized this protein as an RNA binding protein with the ability to associate with Topoisomerase I and the polypyrimidine tract-binding protein associated splicing factor (PSF) [ 16 17 18 19 20 ] . Further, we observed the association of nmt55/p54 nrbwith several splicing factors known to be essential for spliceosome formation suggesting a role for nmt55/p54 nrbin pre-mRNA splicing (unpublished results).

  • Furthermore, exon sequences, outside of the proto-splice site, may be required for splice site recognition by the spliceosome [ 34 35 36 37 38 ] . Our rRNA analyses suggest that G-rich regions in the neighborhood (often upstream) of the intron insertion sites may be potential ESEs.

  • It is also conceivable that proto-splice sites may differ between lineages reflecting, for example, differences in how the spliceosome recognizes introns (e.g.


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