Words similar to spliceosomal
Example sentences for: spliceosomal
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This result provides strong support for the hypothesis that Euascomycetes spliceosomal introns are fixed in a proto-splice site that pre-dates intron insertion.
Group II introns were first identified in fungal mitochondria and grouped on the basis of their secondary structures [ 2 4 5 ] . They have been found in organelle genomes of fungi and plants and also in a number of bacteria [ 6 ] . None have been found in animals, although it has been suggested that group II introns may be progenitors of nuclear spliceosomal introns based on similarities between nuclear pre-mRNA splicing in eukaryotes and the splicing mechanism used by group II introns [ 7 8 ] .
Transcription of these genes is followed by RNA-splicing that results in intron removal (for review, see [ 1 ] ). The majority of eukaryotic spliceosomal introns interrupt pre-mRNA in the nucleus and are removed by a ribonucleoprotein complex, termed the spliceosome.
The spliceosomal introns described in Bhattacharya et al.
Statistical methods were used to study the exon sequences flanking 49 different spliceosomal intron insertion sites in Euascomycetes rRNA and show that the introns interrupt the G - intron - G (hereafter, the intron position is shown with -) proto-splice site that pre-existed in the coding region.