Words similar to sphingomyelin
Example sentences for: sphingomyelin
How can you use “sphingomyelin” in a sentence? Here are some example sentences to help you improve your vocabulary:
L-α-phosphatidylethanolamine, L-α-phosphatidylcholine, L-α-phosphatidyl-L-serine, L-α-phosphatidylinositol, L-α-phosphatidylinositol 4,5-biphosphate, sphingomyelin were identified by using a standard solution.
Sphingomyelin content and luteal cell membrane fluidity decrease during luteolysis in vivo [ 48 49 50 51 ] . Ceramide, a product of sphingomyelin hydrolysis, is a potent stress-activated second messenger and is well established as a functional component of death receptor-mediated apoptosis [ 52 53 54 ] . Upon treatment of CLENDO cells with TNFα, we observed a rapid and sustained increase in the production of ceramide, suggesting that the sphingomyelin pathway is present and active in these cells.
Interestingly, we find that two different cytokines ( i.e. sFasL and TNFα) can activate the sphingomyelin pathway in two distinct CL cell types.
Interestingly it has been demonstrated that rapid production of ROS in endothelial cells exposed to TNFα is mediated by ceramide [ 32 ] . Ceramide is a central figure in the sphingomyelin pathway, which has also been linked to stress related signaling and apoptosis [ 33 34 ] . This report provides evidence that cytokines regulate the fate of CLENDO cells.
The ratios of 24:0/22:0 in sphingomyelin and PS/PI, 24:1n9/22:1n9 in PS/PI and CL, 22:4n6/20:4n6 in PC, PE, and CL, and 22:5n3/20:5n3 in PC and PE, were all reduced by FISH, whereas FUNG had either a neutral effect or partly reversed effects seen with FISH (with exception of CL 24:1n9/22:1n9 ratio).
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