Example sentences for: sphingomyelin

How can you use “sphingomyelin” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • L-α-phosphatidylethanolamine, L-α-phosphatidylcholine, L-α-phosphatidyl-L-serine, L-α-phosphatidylinositol, L-α-phosphatidylinositol 4,5-biphosphate, sphingomyelin were identified by using a standard solution.

  • The ratios of 24:0/22:0 in sphingomyelin and PS/PI, 24:1n9/22:1n9 in PS/PI and CL, 22:4n6/20:4n6 in PC, PE, and CL, and 22:5n3/20:5n3 in PC and PE, were all reduced by FISH, whereas FUNG had either a neutral effect or partly reversed effects seen with FISH (with exception of CL 24:1n9/22:1n9 ratio).

  • The ratio of 18:1n7/16:1n7 in sphingomyelin was decreased by FUNG and FUNG+FISH; in PC, PE, and CL only FUNG feeding decreased the 18:1n7/16:1n7 ratio.

  • Interestingly it has been demonstrated that rapid production of ROS in endothelial cells exposed to TNFα is mediated by ceramide [ 32 ] . Ceramide is a central figure in the sphingomyelin pathway, which has also been linked to stress related signaling and apoptosis [ 33 34 ] . This report provides evidence that cytokines regulate the fate of CLENDO cells.

  • Sphingomyelin content and luteal cell membrane fluidity decrease during luteolysis in vivo [ 48 49 50 51 ] . Ceramide, a product of sphingomyelin hydrolysis, is a potent stress-activated second messenger and is well established as a functional component of death receptor-mediated apoptosis [ 52 53 54 ] . Upon treatment of CLENDO cells with TNFα, we observed a rapid and sustained increase in the production of ceramide, suggesting that the sphingomyelin pathway is present and active in these cells.


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