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Example sentences for: speb

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The results present in figure 5indicate that the kidney-recovered variant was significantly more virulent than the sagA/pel mutant from which it was originally selected (p = 0.018) despite not secreting SpeB or SK in culture (see Table 2).
Selection of SpeB negative variants have also been noted following sequential human blood passage of isolates or in a mouse skin infection model [ 39 41 ] . This selective pressure can also be associated with enhanced capsular expression in SpeB negative variants [ 42 ] .
Analysis of culture supernatants for the presence of SpeB (Fig.
This kidney-recovered variant restored SLS activity, and M and M-related protein expression but not SpeB or streptokinase (SK) secretion.
Previous studies have demonstrated that the inactivation of the sagA/pel gene product also effects expression of other key streptococcal products, including surface M proteins, streptokinase (SK) and the secreted cysteine protease, SpeB [ 4 ] . Analysis of SpeB, SK and M and M-related proteins was conducted to determine if restoration of the expression of the large sagA/pel transcript also reverted the other phenotypes associated with the wild type organism.