Example sentences for: sparc

How can you use “sparc” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Although SPARC is expressed in fibroblasts and macrophages at wound sites [ 18 ] and functions in many processes important to wound repair, the role of SPARC in wound healing in a whole animal has not yet been studied.

  • The results indicate that SPARC regulates wound healing directly through cell migration.

  • Windows didn't run on a Sparc.

  • Mesangial cells, adult skin fibroblasts and smooth muscle cells from SPARC-null mice proliferate faster than their respective wild-type counterparts in media containing fetal bovine serum (FBS) [ 17 ] . Although embryonic fibroblasts from the SPARC-null mice grow at the same rate as the wild-type cells when they are cultured in FBS, the SPARC-null embryonic fibroblasts exhibit down-regulated proliferation as compared to the wild-type cells when the fibroblasts are cultured in serum-free medium containing insulin as the sole mitogenic factor [ 16 ] . Thus, it appears that the role of SPARC in cell proliferation is cell type and environment dependent.

  • Although SPARC is required for migration of dermal fibroblasts into the wound site, it is apparently not essential to the motility of keratinocytes since reepithelialization appears normal in SPARC-null mice.


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