Example sentences for: sparc-null

How can you use “sparc-null” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the SPARC-null mice scabs were thicker and extravasation of blood, visible in the gaps within the scabs, was more frequent and extensive than that in the control mice.

  • These results together show that indeed cell motility, rather than cell proliferation, is the major factor in the retarded wound repair process in SPARC-null cells.

  • Primary dermal fibroblasts from SPARC-null mice contracted type I collagen gels as efficiently as primary dermal fibroblasts from wild-type mice, contracting to 30% of the initial area at 20 hours and to 15% by 40 hours after incubation of the fibroblasts in collagen gels (Fig.

  • Wild-type and SPARC-null dermal fibroblasts were plated in 96-well plates (1 × 10 4cells/well) and cultured overnight in DMEM containing 10% FBS.

  • The wound in a monolayer of SPARC-null fibroblasts, whether cultured in the presence of mitomycin C or in its absence, remained unrepaired at 15 hours, began to show slight closure at 24 hours and healed by 48 hours (Fig.


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