Example sentences for: sparc-null

How can you use “sparc-null” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Previously, SPARC has been shown to regulate cell-cell contact through tyrosine phosphorylation of adherens junction proteins [ 32 ] . Electron microscopy of the SPARC-null dermal fibroblasts at wound sites should not only confirm the role of SPARC in cell motility but also reveal how SPARC mediates cell-ECM and cell-cell interactions to promote cell motility.

  • Wound healing in SPARC-null mice is retarded due to delayed granulation tissue formation.

  • Furthermore, histological examination of new epidermal cells in the wound bed and Northern analysis of expression of a wound keratinocyte marker, cytokeratin 14, in the biopsied tissues revealed that reepithelialization in SPARC-null mice was probably not compromised.

  • Impaired wound repair by cultured SPARC-null fibroblasts

  • Analysis of α1(I) collagen and fibronectin transcripts, which are synthesized by fibroblasts of dermal granulation tissue [ 25 26 27 ] , revealed that expression of both transcripts was delayed in the wounds of SPARC-null mice relative to those of wild-type mice (Fig.


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