Words similar to sparc-null
Example sentences for: sparc-null
How can you use “sparc-null” in a sentence? Here are some example sentences to help you improve your vocabulary:
Previously, SPARC has been shown to regulate cell-cell contact through tyrosine phosphorylation of adherens junction proteins [ 32 ] . Electron microscopy of the SPARC-null dermal fibroblasts at wound sites should not only confirm the role of SPARC in cell motility but also reveal how SPARC mediates cell-ECM and cell-cell interactions to promote cell motility.
Subsequently, the wound in the null mice was fully invaded by fibroblasts and expression of type I collagen and fibronectin by the SPARC-null mice was as abundant as that by the wild-type mice.
One day after surgery a clear thin film of dried exudate covered the wounds in the wild-type and SPARC-null mice.
In the absence of SPARC, expression of transforming growth factor-β1 and type I collagen is down-regulated in kidney mesangial cells [ 15 ] . The expression of cell surface receptor for insulin-like growth factor I in SPARC-null embryonic fibroblasts is also diminished [ 16 ] . Studies with SPARC-null cells have confirmed that SPARC functions in cell proliferation.
Both wild-type and SPARC-null primary dermal fibroblasts were seeded in 6-well plates (5 × 10 5cells/well), and grown to confluence overnight in DMEM containing 10% FBS.