Words similar to spam
Example sentences for: spam
How can you use “spam” in a sentence? Here are some example sentences to help you improve your vocabulary:
The latter is not surprising because (1) Western analysis showed SPAM1 levels to be the lowest in the vas deferens and (2) it is reasonable to expect that HASGE is less sensitive than Western analysis.
Unlike somatic ubiquitous hyaluronidases that are active only at acidic pH [ 8 ] , SPAM1 has hyaluronidase activity at both neutral and acidic pHs, which arise from two different regions within the hyaluronidase domain [ 4 ] . The neutral enzyme activity, which is predominant in insoluble membrane-bound SPAM1, is necessary for sperm to penetrate the hyaluronic acid (HA)-rich extracellular matrix of the cumulus cells surrounding the oocyte.
Variations in glycosylation patterns have been shown to exist among tissues [ 31 ] and glycosylation levels have been reported to influence hyaluronidase activity of SPAM1 in the mouse and horse [ 10 32 ] . Note that in the mouse, tissue differences in glycosylation patterns have been reported for the testis and epididymis [ 33 ] . It is possible that in the epididymis and vas deferens instead of hyaluronidase activity, a more important role of SPAM1 (which is a glycosidase) may be to modify surface proteins of sperm during their maturation.
It is likely that SPAM1 may play a role in sperm maturation, since its expression is highest in the corpus where a number of maturational changes occur [ 41 42 ] . Thus, this study increases the biomedical significance of findings regarding Spam1 in the mouse model.
Importantly, sequencing verified the products to be SPAM1.
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