Example sentences for: signalling

How can you use “signalling” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This complex is thought to be involved in signalling at the cell membrane [ 5].

  • We speculate that, during this period, the inhibitor is entering the cell and altering the expression of components of the IL-1 signalling pathway.

  • However, CD81 signalling could induce the switching of some IFNγ-producing (Th1) T cells to IL-4-producing (Th2) T cells over time.

  • Most frequently, poor MHCII inducibility in response to IFNg has been attributed to alterations in the IFNg signalling pathway and epigenetic silencing of gene expression (reviewed in Ref [ 13 ] ). The cascade of IFNg signalling events leading to transcription activation of MHCII genes has been characterized in great detail (reviewed in Ref [ 30 ] ). Binding of IFNg to its receptor results in JAK-mediated phosphorylation of STAT1 on Tyrosine 701.

  • In addition, IFNg interaction with the receptor leads to p38MAPK-mediated phosphorylation of STAT1 on Serine 727 [ 17 ] . The phosphorylated STAT1 dimerizes and translocates into the nucleus where it activates transcription of several other factors including CIITA [ 31 ] . Although the results of this study do not allow us to describe the exact mechanism of PMA involvement in IFNg signalling in LS1034 cell, at least two non-mutually exclusive scenarios can be hypothesized:


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