Words similar to signalling
Example sentences for: signalling
How can you use “signalling” in a sentence? Here are some example sentences to help you improve your vocabulary:
This complex is thought to be involved in signalling at the cell membrane [ 5].
We speculate that, during this period, the inhibitor is entering the cell and altering the expression of components of the IL-1 signalling pathway.
However, CD81 signalling could induce the switching of some IFNγ-producing (Th1) T cells to IL-4-producing (Th2) T cells over time.
Most frequently, poor MHCII inducibility in response to IFNg has been attributed to alterations in the IFNg signalling pathway and epigenetic silencing of gene expression (reviewed in Ref [ 13 ] ). The cascade of IFNg signalling events leading to transcription activation of MHCII genes has been characterized in great detail (reviewed in Ref [ 30 ] ). Binding of IFNg to its receptor results in JAK-mediated phosphorylation of STAT1 on Tyrosine 701.
In addition, IFNg interaction with the receptor leads to p38MAPK-mediated phosphorylation of STAT1 on Serine 727 [ 17 ] . The phosphorylated STAT1 dimerizes and translocates into the nucleus where it activates transcription of several other factors including CIITA [ 31 ] . Although the results of this study do not allow us to describe the exact mechanism of PMA involvement in IFNg signalling in LS1034 cell, at least two non-mutually exclusive scenarios can be hypothesized:
Loading...