Words similar to severe

Example sentences for: severe

How can you use “severe” in a sentence? Here are some example sentences to help you improve your vocabulary:

However, to exclude that a massive hepatitis or a severe inflammatory infiltrate in the liver is causing the difference of luciferase expression, the inflammatory infiltration and pathological changes were determined in the liver of the two rat strains (Table 5).
Severe chronic illness was more common in non-survivors, especially liver disease.
. Partisan reaction was severe: Republicans called Callender a "clot-hearted Scot," and Jefferson himself wrote that "the federalists have opened all their sluices of calumny."
The caregiver then ranks the severity of the behavior exhibited on a scale of 1 to 3, with 3 being the most severe.
A correlation between sequence conservation and severe phenotype by RNAi had previously been shown by comparison of C. elegans to genomes from the distant phyla Saccharomyces, Drosophila and human [ 63 64 ] . Here we show a similar trend following detection of homology to expressed genes in other nematode species.