Words similar to severe
Example sentences for: severe
How can you use “severe” in a sentence? Here are some example sentences to help you improve your vocabulary:
Before valve-replacement surgery, her severe pectus excavatum was repaired.
Mice at 18 or 19 months had no more than a moderate loss of RGCs, and only 1 of 11 mice older than 20 months had severe RGC loss.
2 locus [ 9 ] . Mutations in the LMNA gene associated with DCM have a more severe prognosis and higher-event rates compared to individuals with DCM that do not have LMNA mutations [ 20 ] . A recent report describing another family with a LMNA mutation causing DCM and conduction system disease documents the need for permanent pacemaker implantation [ 21 ] . Previous reports on the proband's kindred support a high-event rate in family members often resulting in sudden cardiac death even in family members with permanent pacemakers [ 10 ] . For example, ten out of 38 family members with pacemakers for high-grade atrioventricular block died suddenly.
The anti-inflammatory activity of SSZ is due to the 5-aminosalicylic acid component while the majority of the adverse side effects have been attributed to the sulfapyridine moiety [ 14 15 16 ] . Fever, abdominal pain, and rash may develop in 3% to 20% of treated patients, but these side effects are usually mild and improve with dose reduction [ 7 11 12 ] . Severe side effects necessitating SSZ discontinuation occur in less than 5% of treated patients [ 11 ] .
Fluoroquinolones, such as sparfloxacin, of loxacin and ciprofloxacin, are increasingly prescribed in severe cases of traveller's diarrhoea, and have been associated with severe reactions in mefloquine users.
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