Words similar to scaffold
Example sentences for: scaffold
How can you use “scaffold” in a sentence? Here are some example sentences to help you improve your vocabulary:
So possibly, the role of COP1 RING finger in nuclear import is to function as structural scaffold by bringing the two clusters of positively charged amino acids (site 1 and site 3) within the right spatial proximity to fit into the binding sites of the nuclear import machinery, as illustrated by Fig 7C.
In the annotation of the unmasked WGS3 scaffold, transposable elements within rolled introns interfered with Genscan so that a very poor rolled gene prediction was generated, and protein similarity results of transposable elements complicated the evidence.
They have long GC-rich 5'-UTRs that can form extensive secondary structure and have been classified as "weak" mRNAs because they are translated inefficiently when eIF4E levels are limiting (reviewed in [ 15 ] ). It has been proposed that when eIF4E levels are elevated these mRNAs can more effectively recruit eIF4E and its associated factors including eIF4G, a scaffold protein essential in recruiting the small ribosomal subunit, and eIF4A, a helicase essential for scanning through secondary structures in the 5'-UTR [ 15 27 ] .
The sequence of this scaffold is contained within a previously described BAC contig [ 60, 61].
The DLG5 gene encodes for a protein that is a member of the MAGUK (Membrane Associated Guan late Kinase homologs) family of proteins located in the plasma membrane [ 2 ] . MAGUK is a new family of proteins that act as a molecular scaffold for intracellular signaling pathways [ 11 ] . The MAGUK family of proteins is characterized by domains that interact with other proteins to create an assembly of large multi-protein complexes [ 10 ] . The PDZ (PSD-95, DLG and ZO-1) domains are the best characterized for their binding to the C-terminal region of channels and transmembrane proteins [ 11 ] . Usually each protein has 1-3 copies of such domains [ 8 12 13 ] . The SH3 domain (Src homology 3) are present in proteins that couple transmembrane receptors to signaling molecules [ 14 ] . The presence of this domain in MAGUKs increases their possibilities of interacting with signaling pathways.
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