Example sentences for: sca

How can you use “sca” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In (i) a single clone analysis (SCA) the procedure was applied to only one clone at a time, and yielded accurate fingerprints for certain genes experimentally.

  • SCA8 , an untranslated transcript implicated in spinocerebellar ataxia type 8, overlaps the 5' translation and transcription sites of KLHL1 , a gene primarily expressed in the cerebellum [ 12].

  • This conclusion is supported by additional Southern analyses of Sca I digests and Eco RI/ Pst I digests of genomic DNA from the parental diploid, the heterozygotes, and the 54 Arg +Ura +segregants (data not shown).

  • The high throughput only applied to the analysis of the abundance of fingerprints, as in contrast to the SCA, no new fingerprints could be generated by the mixed analysis.

  • Although the formation of intranuclear inclusions has not been observed in previous studies of Ras-related GTPases, it is a common feature of several neurodegenerative disorders where abnormal proteins containing poly-Gln tracts are synthesized as a result of CAG codon expansions [ 52 ] . Examples include Huntington's disease (huntingtin) [ 53 54 ] , spinocerebellar ataxia (SCA) types 1 and 3 (ataxin-1 and ataxin-3) [ 55 56 ] and dentatorubral-pallidoluysian atrophy (atrophin-1) [ 57 ] . These poly-Gln protein aggregates typically contain ubiquitin [ 58 ] and members of the Hsp70 chaperone family [ 59 ] , consistent with a proposed pathway for cellular clearance of toxic misfolded proteins.


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