Example sentences for: scaffolding

How can you use “scaffolding” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In contrast, BCR-mediated activation of Lyn kinase was largely maintained [ 37 38 ] . The Syk-dependent signaling pathway appears to be facilitated by the adaptor molecule BLNK (also known as SLP-65 and BASH) [ 39 40 41 ] . Syk can induce the phosphorylation of BLNK in co-transfection experiments [ 42 ] , which may be important for the recruitment of other Syk substrates like PLCγ2 through a scaffolding function [ 42 ] . BLNK function is necessary for signal transduction since no Ca 2+flux or PLCγ2 phosphorylation is observed in response to BCR engagement in BLNK-deficient DT40 cells [ 43 ] .

  • The network perspective suggests not a single scaffolding protein, but many scaffolding proteins - in fact, a "scaffolding network."

  • PKC may bind to this anchoring protein through displacement of the pseudosubstrate, thus inhibiting the kinase activity, by analogy with a functionally similar scaffolding AKAP, AKAP79 [ 52 ] .

  • His masterpiece, Fallingwater, has been girded by steel scaffolding to prevent it from crumbling.

  • These data suggest that neither a reduction in receptor levels nor a change in receptor association with scaffolding proteins appears to be responsible for the diminished group I mGluR-mediated calcium current modulation observed in the presence of Siah1a.


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