Example sentences for: rxr

How can you use “rxr” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • CAR alone, RXR alone, and CAR/RXR heterodimers bound to various ligands were injected individually into flow cells and binding was measured as described [ 25 26 ] .

  • The xenobiotic receptor CAR (NR1I3) [ 8 9 ] is one of several RXR heterodimers that has not been assigned to either category.

  • Thus, the CAR/RXR heterodimer responds differently to retinoids on different elements.

  • RXR ligands block effects of CAR agonist and inverse agonist ligands on coactivator binding in vitro

  • RAR/RXR binding to nuclear receptor corepressors such as NCoR and SMRT in the absence of ligand inhibits activation of RA responsive genes [ 3 4 ] . Ligand binding displaces the repressors and recruits coactivator proteins such as CBP which have histone acetyltransferase activity [ 5 ] . Histone acetylation allows for chromatin unwinding and transcriptional initiation of target gene expression [ 6 ] .


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