Words similar to rxr

Example sentences for: rxr

How can you use “rxr” in a sentence? Here are some example sentences to help you improve your vocabulary:

This effect was not due to RXR homodimer function, since no transactivation was observed with RXR alone.
All of these observations are consistent with the idea that upon exposure to T-RA there is an early transcriptional response in which a RARγ2/RXR heterodimer activates genes required for differentiation.
Initial studies were based on a well characterized binding site for CAR/RXR heterodimers, the DR-5 element from the promoter of the retinoic acid receptor β2 isoform [ 8 9 16 ] . In agreement with the biochemical results, the rexinoid blocked both the stimulatory effect of the agonist and the inhibitory effect of the inverse agonist on this element (Fig.
The effects of the vitamin A metabolite retinoic acid (RA) are mediated by two classes of ligand dependent transcription factors, the retinoic acid receptors (RAR) and the retinoid X receptors (RXR) [ 1 ] . The RARs are activated by all trans RA and 9-cis RA whereas the RXRs are activated by 9-cis RA only.
The outcome of this inhibition of CAR ligand binding would be somewhat different depending on whether or not the RXR agonist was able to activate the basal transactivation of CAR/RXR heterodimer bound to a particular element.