Words similar to rxr

Example sentences for: rxr

How can you use “rxr” in a sentence? Here are some example sentences to help you improve your vocabulary:

RAR/RXR binding to nuclear receptor corepressors such as NCoR and SMRT in the absence of ligand inhibits activation of RA responsive genes [ 3 4 ] . Ligand binding displaces the repressors and recruits coactivator proteins such as CBP which have histone acetyltransferase activity [ 5 ] . Histone acetylation allows for chromatin unwinding and transcriptional initiation of target gene expression [ 6 ] .
On the βRARE, for example, the RXR agonist might bind, but not increase transactivation beyond that observed in the absence of ligands.
Overall, we conclude that binding of both the DNA and the RXR ligands can result in allosteric effects on the function of the CAR/RXR heterodimer.
Nonetheless, one attractive possibility is that binding of the RXR agonist exerts direct inhibitory effects on either the binding or functional effects of the CAR ligands.
RXR, retinoid X receptor