Words similar to rxr
Example sentences for: rxr
How can you use “rxr” in a sentence? Here are some example sentences to help you improve your vocabulary:
The family of retinoic acid receptors includes those that bind only all-trans retinoic acid (RAR α,β,γ and those that bind either all-trans retinoic acid or 9-cis retinoic acid (RXR α,β,γ Since the transcriptional regulation of the retinoic acid ligand/receptor complex appears to involve the binding of receptor heterodimers (RAR/RXR), the specific cellular response may depend on the ratio of all-trans to 9-cis retinoic acid formed, as well as the expression of receptor subtypes.
Upon exposure to the ecdysone analog muristerone A (murA), the VgEcR/RXR complex efficiently induces the expression of reporter genes in mammalian cells and transgenic animals.
It is interesting that these two CYP elements respond somewhat differently to RXR cotransfection, which increases responses directed by the CYP3A4 element but modestly decreases responses of the CYP2B10 element (data not shown).
The results described here also suggest that rexinoids may have modulatory effects on xenobiotic responses, and that such effects may differ for different CAR/RXR target genes.
In the case of the CYP3A4 response element, however, activation by the RXR agonist is comparable to that observed with TCPOBOP alone.