Words similar to rsv-infected

Example sentences for: rsv-infected

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Biochemical reconstitution studies using purified recombinant actin in vitro and studies in RSV-infected cells ( ex vivo ) demonstrated that actin functions as a viral transcription factor in both monomeric (G) and filamentous (F) forms, whereas the filamentous form appeared to be particularly important for viral morphogenesis [ 10 ] . Subsequent studies showed that at saturating actin concentration, profilin stimulated viral transcription even further, whereas profilin by itself had no transcriptional activity in the absence of actin [ 11 ] . These results suggested that the interaction of profilin with actin may be important for optimal activity of the RSV transcriptase.
We then tested whether profilin interacts with viral proteins in the RSV-infected cell.
In contrast, stress fibers were completely absent in RSV-infected A549 cells (Fig.
Because profilin stimulated RSV transcription in vitro [ 11 ] and associated with viral transcriptional proteins, N and P, the obvious next question was to ask how important profilin was for viral gene expression in the intact RSV-infected cell.
An extract of the RSV-infected A549 cells was first subjected to immunoprecipitation by anti-P antibody and the precipitated proteins probed in immunoblot with profilin antibody.