Words similar to rsv
Example sentences for: rsv
How can you use “rsv” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, the inhibitory effects were most striking for Rel A suggesting the inhibitors primarily target the RSV induction of Rel A.
It should be noted that besides profilin, there are many other cellular proteins known to modulate actin filamentation and cytoskeletal dynamics, and profilin itself binds to a large number proteins, many with poly-proline sequences [ 42 43 ] . Clearly, identification of the various members of the cytoskeletal signaling pathway will constitute an important step in understanding host-RSV interaction, and may lead to additional targets for pathological intervention.
Moreover, the functional viral RdRP, as detailed later for RSV, is a complex holoenzyme composed of viral as well as cellular proteins [ 17 18 19 20 21 22 23 ] . Second, many NNR viral genomes and proteins are currently expressed from vaccinia-based cDNA clones, which generally requires superinfection by vaccinia virus [ 22 23 ] . Unfortunately, vaccinia virus itself is a major modulator of cellular signaling, including MAP kinase pathways and the actin cytoskeleton [ 24 25 26 ] . It is, therefore, virtually impossible to study the interaction between cellular signaling pathways and NNR viruses in cells that are also superinfected by vaccinia virus [ 24 25 26 ] . Third, mutations in the recombinant DNA are "permanent", and thus, the mutational phenotype cannot be switched on at pre-determined time points in infection.
The ability of soluble monomeric G-actin to polymerize into filamentous F-actin in a reversible manner is central to the cellular function of actin [ 1 2 ] . Rearrangement of actin is promoted rapidly by extracellular stimuli, and is facilitated by sets of actin-associated proteins, one of which is profilin [ 2 ] . It is now appreciated that a large number of cellular parasites co-opt actin for their gene expression and replication in the host cell [ 3 4 ] . Due to its primary role in pediatric respiratory disease, and the enormous human and economic toll it exacts throughout the world, the respiratory syncytial virus (RSV) and its interaction with the host cell have received serious attention.
Our findings suggest that RSV induction of chemokine gene expression involves a redox-sensitive NF-κB signaling mechanism that differs from that mediated by TNFα and involving predominantly the Rel A subunit of NF-κB.
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