Example sentences for: ro

How can you use “ro” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This did not appear to be the case, as the effect of CD81 was most prominent on CD45RO +cells, which do not include naïve T cells.

  • Because the effect of CD81 on IL-4-producing T cells was most dramatic with CD45RO +cells (Figure 4C), it was hypothesized that CD81 costimulation was affecting the number of IL-4-producing memory T cells over time.

  • Although the naïve/memory phenotype of T cells has previously been investigated in RA in numerous studies using CD45RA and CD45RO expression as markers of naïve and memory cells, respectively, that approach has suffered from the limitation that large numbers of CD45RA +CD8 +T cells are actually effector memory cells [ 10 13 ] . The CD45RA/CD45RO oversimplification has also resulted in rather confusing conclusions regarding T-cell homeostasis, such as defects in primary T-cell homeostasis based on reduced T-cell receptor excision circle (TREC) levels in naïve CD4 +T cells (defined as CD45RO -) in RA patients [ 14 ] . Our findings suggest that reduced TREC levels in the CD45RO -CD4 +T-cell population may not be due to a reduction in TRECs in naïve cells but rather to reduced TRECs in the CD45RA +CD45RO -CD62L -effector memory CD4 +T cells.

  • Frequencies of CD4 +memory T cells that expressed cytokine and activation marker mRNA are shown in Table 6. IL-2, IL-4, IL-6, and LT-α were not expressed by the RA peripheral blood CD4 +CD45RO +T cells, whereas 4-17% of cells expressed the other markers.

  • IL-2, IL-4, IL-6, and LT-α were not expressed by the peripheral CD4 +CD45RO +T cells, whereas 4-17% of cells expressed the other markers.


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