Example sentences for: roc

How can you use “roc” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In addition to the key roles in E3 ligase activity, RING finger domains have also been shown to be important for regulating subcellular localization of E3s and/or their substrates in a number of cases [ 53 54 55 56 ] . Studies have shown the MDM2 RING finger domain is required to promote nuclear export of p53 and this activity of MDM2 RING finger seems to be coupled with its ability to promote ubiquitination of p53 [ 53 54 55 ] . Rbx1/ROC1, the small RING finger subunit of the SCF E3 complexes, promotes the nuclear accumulation of Cul1, another subunit of the SCF complexes [ 56 ] . These studies have suggested a correlation between the ubiquitination activities of RING fingers and their roles in regulating subcellular localization of the E3 ligases which they are part of.

  • The area under the ROC plot is an estimator of the discriminatory power of selecting a cut-off and varies from array to array.

  • Areas under the ROC curve have been reported to range from 0.65 to 0.77 in case series comprised of patients enrolled in screening trials [ 4 19 20 21 ] or followed in urologic practice [ 22 ] . Among urologic studies, we found only Labrie and colleagues reporting a substantially higher area under the ROC curve: 0.88 (SE 0.03) [ 23 ] . However, biopsies were performed only when digital rectal or transrectal ultrasound examinations were abnormal, which would inflate the apparent sensitivity of an elevated PSA level.

  • For complicated situations, Baker [ 16 ] proposed an algorithm to select the regions creating the best ROC curve without the need to enumerate all the regions.

  • There were no statistically significant differences in the correct prediction of outcome, Youden index or area under the ROC curve among APACHE II, MEES and GCS for hospital mortality.


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