Words similar to riiβ
Example sentences for: riiβ
How can you use “riiβ” in a sentence? Here are some example sentences to help you improve your vocabulary:
No consensus C/EBPβ binding site is found in the promoter construct responsive to cAMP and C/EBPβ, but a possibility exists that C/EBPβ attach to the RIIβ promoter through protein/protein interactions with USF1 or other members of the transcriptional unit formed at the E-box.
USF1, however, had no inhibitory effect on the cAMP-mediated induction of RIIβ.
We have previously shown that C/EBPβ functions as a secondary effector of cAMP signaling on slow response genes in Sertoli cells, including RIIβ [ 17 ] . Both C/EBP and the RIIβ E-box is shown be involved in cAMP responsiveness of the RIIβ gene [ 17 18 ] .
A reporter construct containing the basal promoter of the rat RIIβ 5'-flanking region (-394 to -123) upstream of a CAT-reporter gene (pCATbasic; Promega, Madison, WI) was used for assaying RIIβ promoter activity [ 18 ] . Expression vectors for USF1, USF2a and USF2b inserted 3' of the CMV promoter in pCR™3 (Invitrogen, Groningen, The Netherlands) were used to overexpress USF isoforms [ 12 ] . C/EBPβ LAP (full-length) and LIP (DNA-binding domain) expression vectors created in pCMV™3 (Stratagene, La Jolla, CA) were appreciated gifts from Dr. Shizua Akira (Hyogo College of Medicine, Hyogo, Japan).
3. Overexpression of USF2, but not USF1, inhibits cAMP-mediated and C/EBPβ-mediated induction of the RIIβ promoter.