Example sentences for: rii

How can you use “rii” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For keloid fibroblasts, the size and granularity of the α-SMA expressing cells was similar to those expressing ED-A fibronectin rather than TGFβ1-RII (not shown, please, see additional file 2: Additional data #2.ppt).

  • For PKA binding, it was thought for a long time that only RII subunits bind to AKAPs.

  • However, a new class of AKAPs was discovered when two dual-specific AKAPs (D-AKAP1 and D-AKAP2) were cloned using a fusion protein of the RIα as the bait in a yeast two-hybrid screen [ 15 16 ] ). Therefore, the contrasted distribution pattern between RI and RII may in part be due to selective association with different compartmentalized pools of AKAPs.

  • However, a recent study showing the colocalization of D-AKAP1 with RI at the NMJ supports the prediction that localization of the R subunit there requires interaction with an AKAP [ 17 ] . RII has been shown to be associated with mAKAP in heart and skeletal muscle [ 20 21 ] ; however, little is known regarding the expression patterns of RII and AKAPs in the perijunctional regions.

  • We therefore measured the expression of α-SMA together with of the expression of those proteins participating in the initial signal transduction event: TGFβ1, its type II receptor (TGFβ1-RII), and ED-A fibronectin.


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