Words similar to riiα
Example sentences for: riiα
How can you use “riiα” in a sentence? Here are some example sentences to help you improve your vocabulary:
RIIα localized quite well to mitochondria in both NMJ and muscle regions.
PKA association with mitochondria has been well documented [ 38 39 40 41 42 ] . In mammalian sperm, it was found that nearly all RII-specific labeling was with mitochondria [ 43 ] . Furthermore, in bovine heart, PKA activity was detected in the matrix or the matrix side of the mitochondrial inner membrane [ 44 45 ] . However, the work of Halestrap and coworkers provided little evidence for intramitochondrial protein phosphorylation by PKA, but gave some evidence for outer membrane phosphorylation, both integral and loosely bound proteins [ 46 47 48 ] . The localization of RIIα to the postsynaptic region beyond the postsynaptic membrane is consistent with part of the immunostaining of NMJs in the soleus muscle [ 18 ] , yet differs in part because there is no overlap with the bungarotoxin label; however, this is in agreement with another study [ 17 ] .
We found that the labeling patterns for these two antibodies in muscle tissue counterstained with bungarotoxin and anti-D-AKAP1 (data not shown) was not modified from that found when counterstained with bungarotoxin and a mitochondrial marker (see below), indicating partial colocalization of D-AKAP1 with RIIα but, little if any overlap with RIIβ.
Of the 7 kinase and AKAP labeling patterns shown in this paper, RIIα is the only one that strongly associates with the z-line (contrast with the phalloidin labeling shown in fig.
Mouse anti-PKA RIα, mouse anti-PKA RIIβ, and mouse anti-PKA RIIα were purchased from Transduction Laboratories.