Example sentences for: ribosomes

How can you use “ribosomes” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The proper assembly of basic proteins with nucleic acids, such as occurs in the packaging of histones with DNA to produce chromatin and in the packaging of ribosomal proteins with rRNA to form ribosomes, is a reaction that must be facilitated so as to prevent the aggregation of these oppositely charged groups of molecules.

  • More ribosomes were found to be associated with countin mRNA in early developing Ax4 cells relative to BS153 cells, which is the converse ribosome association with bulk mRNA in the two strains.

  • At present, in contrast to studies on bacterial and archael ribosomes, relatively little is known about the functions of individual mammalian ribosomal proteins ( [ 42 ] . However, assuming that changes in message abundance lead to alterations in protein levels, it is reasonable to anticipate that the NGF-promoted effects observed here may affect the protein synthetic capacity of the cell in some manner.

  • Early studies indicated that depletion of amino acids and not other nutrients is essential for initiation of development [ 19 20 21 ] . Upon amino acid starvation, among other events there is a substantial decrease in the rate of initiation of protein synthesis, resulting in a reduction in size and amount of polysomes and accumulation of free ribosomes [ 19 22 23 ] . It is believed that the decrease in protein synthesis in response to starvation occurs post-transcriptionally, since adding back amino acids rapidly restores protein synthesis and does not require new mRNA synthesis [ 22 ] .

  • A very early event marking the initiation of development is a substantial reduction in overall translation initiation and a concomitant major shift of ribosomes from mRNA-associated ribosomes (polysomes) to free ribosomes [ 22 23 ] . The percentage of mRNA associated with polysomes drops from about 80-90% in growing cells to 50-60% within several minutes of the removal of the food source.


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