Words similar to rett

Example sentences for: rett

How can you use “rett” in a sentence? Here are some example sentences to help you improve your vocabulary:

To identify potential downstream targets of MeCP2 modulation, we have compared global gene expression patterns in four matched pairs of clonally derived mutant or wild-type MECP2-expressing fibroblast cell strains from girls with Rett syndrome, and in five wild-type and four mutant MeCP2-expressing lymphoblastoid cell lines, by hybridizing Affymetrix U95 (A-E) oligonucleotide microarrays.
Much to our surprise, expression levels of 5 genes in 11 additional MeCP2-deficient and 11 additional MeCP2-positive clones from two Rett individuals, one with a missense and one with a truncating mutation, showed tremendous variation.
Second, if the inter-clonal variation we detected by the quantitative RT-PCR study of 5 genes in 22 clones from two different Rett individuals were representative of a general feature of diploid fibroblast clones, it could have masked any consistent biologically meaningful expression changes.
Clonal mutant and wild-type MECP2 expressing fibroblast cell strains were successfully established from four Rett females with different mutations, one missense in the MBD, one missense in the TRD and two frameshift mutations leading to premature stop codons.
Expression of CRIP1 was significantly different between wild-type and mutant clones for both Rett individuals tested (p = 0.004 and p = 0.035), however, the direction of change was different.