Example sentences for: retrotransposition

How can you use “retrotransposition” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The translation for each full-length L1 sequence was analyzed for the presence of nonsense mutations, and for missense mutations that inhibit retrotransposition activity by destroying the catalytic sites of the endonuclease or reverse transcriptase or any other critical residues on which retrotransposition depends (see Materials and methods for a complete list) [ 12, 14, 46].

  • At least one novel gene, the CG2222 -like gene D. willistoni , is likely to have originated from a retrotransposition event as this gene lacks introns while its closest homolog, found on a different chromosome arm in the D. melanogaster genome, has two introns.

  • Relatively recent retrotransposition events can be recognized in genomic DNA with computational sequence analysis tools; however, the precise determination of the boundaries of L1 elements is complicated by the highly variable sequence and anatomy of L1 insertions.

  • Recent analyses suggest that 70% of non-functional duplicated genes (pseudogenes) in the human genome result from retrotransposition rather than any DNA-based process (Torrents et al.

  • Full-length L1s are capable of autonomous retrotransposition.


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