Words similar to retinoids

Example sentences for: retinoids

How can you use “retinoids” in a sentence? Here are some example sentences to help you improve your vocabulary:

Similarly, retinoids can upregulate TGF-β production and activation, both in cell culture and in rats in vivo [ 16, 17].
Retinoic acid receptors (RARs) and retinoid X receptors (RXRs) are nuclear transcription factors that mediate the action of retinoids [ 11 12 ] . We have demonstrated that in the rat, castration resulted in an increase in mRNAs for RAR α and γ in the prostate; such effects were prevented by T replacement [ 13 ] . We also demonstrated that the levels of mRNAs for RAR α and γ in non-tumorigenic rat epithelial cells (NRP152) were down-regulated, whereas those in tumorigenic cells (NRP154) were unaffected or up-regulated following T treatment [ 14 ] . In addition, RAR α was over-expressed in tumorigenic NRP154 cells.
To date, expression of TGF-β receptors and downstream signaling components such as the Smads have not been well-characterized in this rat model, but in our preliminary analyses we saw no effect of retinoids on type I and type II TGF-β receptor expression in the mammary gland (data not shown).
Thus, part of the chemopreventive efficacy of antiestrogens and retinoids in this model may be due to a generalized decrease in ductal development.
We saw a lesser effect with 4-HPR, although this type of phenomenon has also been described in the literature for retinoids [ 4].